Gout is mainly due to a purine Anabolism is a recurrent inflammatory disease in the joints, and it is also more frequent in daily life. In daily life, it mainly produces some hyperuricemia, and always produces some gout-related nephritis. And functional disorders of joint deformities, mainly primaryThe main symptoms of the secondary and secondary symptoms are joint pain and often occur in minor injuries or overeating.
Some key points after the impact of related diseases. It is mainly to remove some gout joint systems that affect functional activities for treatment. Dietary health care is also very important, adjusting the diet structure, prohibiting tobacco and alcohol, and reducing weight.
Gout is caused by increased purine biosynthesis, excessive production of uric acid or poor excretion of uric acid, resulting in increased blood uric acid, and urate crystals are deposited on joint slips. Recurrent inflammatory diseases caused by membranes, bursae, cartilage and other tissues. It is caused by monosodium urate crystals (MSU) or uric acid forming a supersaturated state in the extracellular fluid, causing the crystals to deposit in the tissues. A group of heterogeneous diseases caused by this disease. This disease is characterized by birefringent sodium urate monohydrate crystals found in synovial fluid and tophi. Its clinical features are: hyperuricemia and urate crystals and deposition The resulting characteristic acute arthritis, tophi, interstitial nephritis, severe joint deformities and dysfunction, often accompanied by uric acid urinary tract stones. The etiology is divided into two categories, primary and secondary.
Acute onset of joint pain is a typical symptom of acute gout. The onset of disease is usually after minor injury, overeating or related diseases. It is especially common in the distal joints of the limbs. The typical symptoms are in the toes (foot gout). It can also cause renal colic due to urate stones. Chronic gout is characterized by destructive joint changes.
Skin symptoms: About 1/2 of the cases, urate is deposited under the skin. These nodules are called gout Nodules or tophi. Tophi are often white or pearl-colored nodules (gout pearls), which occur on the free curved skin edges (such as the auricle). Another characteristic symptom of tophi is that the (toe) joints are white or Yellow nodules. Deposits of urate in the skin. Round stones can be seen through the thinned skin and they may rupture. There are clusters of gout nodules near the joints.The tendency to occur or merge. Tophi occurs after an acute attack and is painless. If the skin is ruptured, white lime-like substances can be released. Microscopic examination shows a carcinogenic mixture of fascicular needle-like substances, which is identified as sodium urate.
The above is the introduction of gout. The treatment to prevent gout and the prevention and treatment of cardiovascular and cerebrovascular and complications are also very important.Diet health care is also very important, adjusting the diet structure and prohibiting tobacco and alcohol and some weight reduction. Therefore, patients who find gout in their daily life must be treated or checked in time.